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The usual story I heard was that the genetic line was purer in the days of Adam and Eve (or something), and so the normal problems with inbreeding didn't arrive. Later on (say, by the time of Noah), the genetics had deteriored so that incest was more problematic. Of course, Christians who view the story as myth don't have these sort of problems
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"Die Deutschen meinen, daß die Kraft sich in Härte und Grausamkeit offenbaren müsse, sie unterwerfen sich dann gerne und mit Bewunderung:[...]. Daß es Kraft giebt in der Milde und Stille, das glauben sie nicht leicht."
"The Germans believe that power must reveal itself in hardness and cruelty and then submit themselves gladly and with admiration[...]. They do not believe readily that there is power in meekness and calm."
-- Friedrich Nietzsche
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