Quote:
Originally posted by sillygirl
And wasn't Ketamine used as a horse tranquilizer? 
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Ketamine and its close cousin PCP are used as such. However, Ketamine does not produce psychotic aggression. In fact, it's used widely as a pain killer and has been successful with treating heroine addiction--in metered doses. As a disassociative, it can cause permanent brain damage, particularly widespread brain cell death by blocking glutamate transmission (glucose is the brain's fuel). K can cause brain lesions--"Olney's Lesions"--and there's currently no way to determine how suseceptible you will be to this.
Disassociatives (of which K is generally the mildest) have been linked to siezures and depression to a much higher degree than other recreational usage drugs. They are a much different beast from LSD, marijuana and shrooms. While the above cause your mind to open to the outer universe, to take down the walls of sensory filtration, disassociatives do the opposite. You can get to the same place, ironically, but you'll come around from the other side of the mental mountain. Your mind will be driven into itself rather than pushed outward.
Those who are prone to siezures or epilepsy--or have a family history as such--must steer very clear of this chemical. If you want disassociation, you can good results with transcendental meditation, which is of course much cheaper and safer, as well as being legal to do anytime and anywhere, in any amount--although even TM has its share of controversy.