You have to confront her. Think about it like this. You love this person and you want her to stick around. You have to confront her because she will continue to hurt your feelings because she's either a jerk and doesn't care or she doesn't know how much stock you place in a certain situation.
When someone hurts your feelings you have to tell them. The chain you speak of is really resentment and grows tighter with time. If a confrontation does not illicit an apology then that just comes to show what kind of person you're living/dealing with. Think about the situation and exactly how relevant/important it is to you and central to your happiness. A lack of apology and resolution will ENSURE it continues.
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