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Essentially it depends on what you have running round the particle accelerator.
Generally you'd be hitting them with a vast ammount of energy, a moderate ammount of high speed (nearly light speed) matter, and probably a large whallop of ionising radiation (unless you generated a neutron beam).
Pretty much, you'd fry them, punch a hole through them, cook them, and give them radiation poisoning at the same time.
That's assuming that they didn't try to move in the hyper-strong magnetic field - which would cause magnetic eddies in the fluids of the body, and cause them to boil.
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Overhead, the Albatross hangs motionless upon the air,
And deep beneath the rolling waves,
In labyrinths of Coral Caves,
The Echo of a distant time
Comes willowing across the sand;
And everthing is Green and Submarine
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