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It is best if you do cardio with no food in you stomach because you will burn fat more efficiently. It is also a good idea to eat a carb/protein meal within thirty minutes after you lift weights as this is crucial for muscle building. So, you can see that if you are going to do cardio right after you lift you will not be as effective at muscle building unless you have a quick meal, and this may inhibit your fat burning during cardio.
I have always separated cardio and lifting except when I want to get to very very low bodyfat levels - then I do cardio after lifting, as well as other times throughout the week. I recommend mixing it up; and remember intensity is what really makes the difference between an average body and a great one.
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