This is an internal IDE I presumed? How old is the motherboard? After all you have done it sounds like the MB is going bad or at least the battery might need to be replaced. Give that a try first, clean the RAM contacts with rubbing alcohol and seat them firmly.
Try to get the latest firmware for the burner if you can. Uninstall Alcohol 120%, use Nero or Daemon Tools instead, see if these two recognize the drive and can burn successfully.
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