A. "Know Thyself". My personal belief would be that it is impossible to know thyself completely until your life is over. You must experience the whole in order to know the whole. This of course would require an afterlife of some sort or a last minute revelation to really be obtainable. I do however believe one can know how they are at a given moment. In my experience we all have ideals, we try to live by then, but undoubtable fail (at least I do, and it's my guess everyone does). By learning from those failures you gain a better understanding of yourself, thus going back to the original question.
B. What we do in the middle... I would personally say that is all that matters. It must come from an internal strive. I would like to believe that the purpose is to advance our race (humans) as a whole to better the world. As this can come in many forms, and be interpreted many ways it all comes back to choice. I know people who fall under the belief that you should strive for what brings pleasure/gratification as it's the natural reward for following your path in life.
All in all, I hope I gave you an insight at least, instead of just raising more questions.
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