I believe Smooth gave you 95% of what you need to know. Only you can decide if this is best handled in person or via e-mail.
My only suggestion would be that you conclude with something to the effect that a good relationship with your co-workers is important both to you and to the office, and you would greatly appreciate any help your boss can provide in resolving the matter.
Management, especially middle management, is almost required to provide help when asked, or have a darn good reason why they didn't provide it.
Disclaimer: I have very little experience in situations such as yours, so perhaps someone else may disagree with what I've said.
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