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If the pill she tries she gains weight on, then try a different one. No doctor would want you to look/be unhealthy for the sake of birth control.
Tell her that there are HUNDREDS of different kinds of pills, and many other alternative solutions. Unless you want a good chance of having a child or pregnancy scare soon, please, just go talk to a doctor or something.
I've been on Depo for almost 2 years and haven't gained any weight - if anything, I've lost some. No other bad side effects.
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