It's one thing to describe homosexuality as a "biological error" in a purely descriptive, scientific context. It's completely another to use that as ammunition for castigating an entire population and denying them basic rights.
There's a difference in context between the comments made by "Dr." Laura and 50Cent:
Dr. Laura is parading as some kind of authority (which is arguable, depsite the Ph.D. behind her name) and her words therefore carry a greater weight - they're more likely to be taken as true. Her criticism of homosexuality was not limited to the few phrases that are being bandied about here. Those phrases were part of a much larger pattern of vitriolic and religious-based (NOT science-based) gay-bashing that was frankly much more insidious than what 50cent said.
50cent is a rapper. Sure, his words reach a lot of people and he should probably consider the impact of them, but he's speaking as an individual - not as a medical authority - and his opinions are likely to be seen as just opinions. And as others have pointed out, he makes a distinction between "wrongness" and his preference not to be around people who are gay. There's a difference between being personally uncomfortable around a certain kind of person, and insisting that their identity is invalid, wrong, etc., because you don't happen to like it.
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"If ten million people believe a foolish thing, it is still a foolish thing."
- Anatole France
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