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Depression occurs for many reasons. Stress, genetics, lack of sufficient sleep, chemical imbalances can all cause depression. Sometimes you can get past it sometimes you can't, depending on what causes your particular depression. I think often meds should be taken in conjuction with therapy lest they become a crutch rather than a cure. Some people are stuck on medication for the rest of their lives because that is the only option that allow them to live a normal life.
There is an emerging area of neorological study whose name eludes me. Its focus is on the brain's ability to rewire itself. Maybe it will have depression treating applications.
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