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I think if natural selection applies it is more on an intellectual level than a physical one.
I don't think that medicine has made us weaker as a species. I guess it depends on how you define weak. The average human life span in an industrialzed nation is longer than ever and keeps increasing. I doubt that overpopulation is a problem you'd associate with a "weak" species(not that it is necesarily sustainable).
As for "natural" v. "artificial", when it comes down to it, this computer that i am typing on is as no more artificial than a bird's nest or an obsidian knife.
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