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okay, and this is coming from another formerly really heavy guy.
keep running. most likely, in my opinion and based only on what you've posted, you don't have an mcl strain. in fact, if i'm remembering my anatomy class right, you're really have to be doing something with my quick turning to really hurt it (if i remember right, can't check it right now though, the mcl and acl help to hold you knee in place the way it is against sideways forces, someone correct me if i'm wrong, it's been awhile). my best guess is that you've got <b>normal aches and pains</b> of body adjustment. why did i just bold that? i don't know. :-)
at one point, i weighed 282 lbs, and i'm only about 5'11" or barely 6' tall. so i was a big son of a b... anyways, especially if you havent' been running before this, it takes your body, especially your joints a little while to become accustomed to the strain of running. i found that the first week or two of running on a track or treadmill would hurt my knees and sometimes ankles when i did it for more than 10 minutes. but after a couple of weeks, it stopped. now i'm 220, and there's not pain when i run.
if you want to take a week off to rest it, fine, but i doubt it's what your trainer said. the best thing to do would probably be to make sure you've got good running shoes (new, preferably) that fit right for you (go to a store that specializes in them, they'll know how to take care of you) and stay off the pavement. either run on a treadmill or the track at a local highschool. both of those will absorb some of the shock and be much better on your knees than pavement will be.
my $0.02.
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