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What I am saying is they aren't naturally found that way. They are created by man.
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This does not dictate anything other than how they were created, it does not dictate "inherit drug safety".
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when is the last time you heard of someone overdosing on marijuana?
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Overdosing is not the same as taking a lethal dose. I have never heard of someone dying as a result of self-administered marijuana (except from people who didn't know what they were talking about), but I have heard and seen and experienced where many a time the person was more stoned than they intended to get.