I'd do it, after all the guinea pig men were done with it to prove it wouldn't have the side-effects of DepoProvera in the article AngelHands linked to. My girlfriend was on the shot, it was cool because she wasn't going to get pregnant... too bad her sex drive was so decreased she didn't want to have sex.
I'm going to wait, but sure seems a better option than a vasectomy. A shot is a shot. It's not like Pinhead from the Hellraiser movies has to give you head.
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