Thank you all for the replies. First, lets just assume that I don't really plan on installing Mozilla or another browser. So that leaves me with two choices, either a software popup blocker or the hosts file method. I have heard of the hosts file before, and used it a long time ago, but it seemed to cause problems in my everyday browsing. Like certain features on certain sites would not load/work correctly. Just one main example that I can remember is that on espn.com using the scoreboard for say NFL or any other sport, I could not use the auto-refresh page. Like if I choose 30-seconds, which means it is suppose to reload the page automatically every 30 seconds, would not work, etc. I am just curious for those of you out there using the hosts file method, if you have many problems such as mine while browsing the internet.
Finally, if I decide against the hosts file idea, I would still like to get the best software popup blocker available, so keep the opinions coming

Thanks.
G_Lock