People create art so they can sell it, or (more likely) because they enjoy creating it. I haven't met an artist that didn't like what they do.
I don't believe it is an oversimplification - people tend to do what makes them feel good. Even self-sacrifice makes people feel warm and fuzzy inside because they know they did the 'noble' thing. Nobody likes pain (anybody who derives pleasure from pain is feeling pleasure, not pain). People will do what it takes to avoid it. The shot is a case of foresight - some pain now to protect against more pain in the future.
And of course, all beings tend towards self preservation.
Biologically speaking, however, there are many inconsisten human behaviors. Laughter, for instance, serves no biological purpose - animals don't laugh. Why are things 'funny'? What could this trait have evolved from? Love, also, is not biologically intuitive. Maternal love, yes, but sexual love is not. Reproduction is more efficient and effective if the two parties are not emotionally attached to each other. In today's society, biologically sound reasoning would be for women to look for the richest, most able-bodied men - not the men with the greatest smile or personalities.
Caring for the elderly and the terminally ill are also counter-intuitive. It is a waste of resources, and in the case of the ill, a weakening of the gene pool. The more sick and weak people we keep alive, the weaker the human race is on the whole.
There is a lot that doesn't make sense in a purely biological sense, which makes many wonder how these behaviors evolved in the first place.
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Sure I have a heart; it's floating in a jar in my closet, along with my tonsils, my appendix, and all of the other useless organs I ripped out.
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