i was a stagegoon for goldenvoice a large local company that produced punk shows in the late 70s early 80s when punk shows were scarier than shit.
you can pull moves on big fast guys but it's gotta work fast and right the first time. i've punched the back of guys hands as they held them up to box me thereby breaking every bone in the back of the hand. i've used aki-jujuitsu moves on guys and i've hit guys with chairs, walls you name it. i'm not that big. 6'1/205lbs, but speed is the shit. now if a huge guy grabbed me and i couldn't get free in a second i'd be dog meet.
my teacher always told me that a good strong nfl player could kick shit on most martial arts guys. i've seen high school wrestlers beat hell on black belts. my favorite scene was down in newport beach i saw some asian guy whip out some tkd on a huge white guy. the white guy caught his leg and preceeded to swing the asian guy multiple times like a baseball bat into a nearby wall. priceless. they probably don't teach a defense for that at tkd school.
as always luck plays a small part in any fight. but yes big good wins out over small good most of the time.
btw youth also plays a factor. i'm over 35 now. watch punk shows safely from the back and pull a muscle reaching for the tv remote too quickly.