For contacts, I would suggest the <a href="http://www.palm.com/us/software/desktop/mac.html">Palm Desktop</a> software. You don't need a Palm to use it and it's relatively powerful.
A more basic solution would be to use AddressBook.framework via Address Book. It's steadily increasing in capabilities and is readily extensible if you want to dabble in the Cocoa programming environment. Plus, it's a framework fully supported by Apple.
For file management, I'm not personally familiar with any programs because I simply use the Finder. However, <a href="http://www.tucows.com/">Tucows</a> gave <a href="http://knet.tucows.com/preview/217958.html">Path Finder</a> a five-cow rating, and Tucows is quite reliable.
If you have an iPod, then I would suggest using Address Book and iCal, since both synchronize not only with your iPod but with the .Mac server. Thus, you can have your contacts and appointments on your iPod or, god forbid you lose it, you can just find an Internet-capable computer.
Good luck, and please let us know what route you choose.
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