Might I suggest a leach instead of a flea? Fleas are kinda... hmm... anticlimactic?
The most important thing in WoD games (im my experience, at least) is to know where you want to take the game and how. I suggest you get your friends to make thier chars ahead of time so you can integrate them into the story and work out some motive for them. In the past I have rewarded people that write me a significant bio with freebie points... helps me by giving me data, helps the player by making thier character more vibrant.
Oh, and keep the players confused as to who to trust... that's always fun