I'd say it would be necessary to speed up the centrifuge gradually to ease the body into it. In the beginning, you'd have to keep activity to a minimum to prevent the heart from being overworked. Eventually, the muscles and bones would build up to handle the new stress. Coming out, the heart would be overworked, like the situations when a 500-pound man has all of it lipo'ed off, and suffers an aneyurism because his heart is now pumping too hard for his body. You would be like the über-chicken, able to lift more, jump higher, and run faster.
I'd be fucked up in the first two hours between the bad back, bad knees, and flat feet.
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