All I do is alcohol and the occasional cuban cigar. Good red wine, single malts and German beers without the preservative shit.
I think its important to know about drugs, even if you don't do them.
www.erowid.org is a really interesting resource, as reading it does makes you realize that just about everything that enters our bodies (by whatever means) has an effect on our minds.
One consequence of criminalizing the chemical drugs is the amount of shit like caffeine that's cut with it on the street. How can you asses the harmfulness of ecstacy when the pills are just as likely to contain god-knows-what in addition to the ecstacy?
I would like to see mainstream academia agree on some kind of research conventions for the study of hallucinogens. It'd really might help in understanding the human brain. It's not going to happen though, they're just too conservative.