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i'm 38 and i've occasionally used drugs over the years. Here's my advice:
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I think your post is pretty neat, but there are a few things that I think must be corrected:
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Erowid, mentioned before, is a great resource. Remember than many street drugs aren't clean, so you may not know what you're getting unless you have a trusted friend helping you. Many drugs (ketamine, nitrous oxide, sniffing glue) can permanently damage your brain with a lot of use. Others (LSD, ecstacy, mushrooms, pot) are generally safe to your body, especially when occasionally experimenting with them. Overuse of anything is bad.
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Ketamine has similar risks to drugs like PCP and DXM. Too much may lead to mental impairment and possibly microscopic vacules (holes) in your brain ("Olney's lesions", named after the scientist who discovered it). Although I do not not if it is possible for even non-human primates to suffer from Olney's lesions due to ketamine/dxm/pcp use, it is clear that impairment most likely will occur. Symptoms of impairment seem to disappear with time.
Nitrous oxide, for all intents and purposes, will not damage your brain. Extremely heavy, chronic use may deplete B12 and lead to other adverse conditions, but this can be avoided by taking B12 whenever you feel like binging on nitrous.
While it is true LSD and mushrooms are not heavily taxing on the body in a way that a drug like meth would be in higher doses, and pot can protect the brain from damage due to stroke or physical trauma, MDMA may be something of more concern. MDMA, taken responsibily and infrequently, is unlikely to cause any adverse physical effects related to neurotoxicity (my own opinion). However, when it is used in a way that reflects the media stereotype of an "Ecstasy" user, MDMA may exacerbate adverse psychological conditions and may adversely affect brain tissue. I think the riskiest part of using MDMA for someone who knows what they are doing is finding it.
All of these are on Erowid.
While one may receive blood borne diseases on the rarest of occasions, it wouldn't be sexually transmitted.