I've been puttering around with ways to integrate all my tech toys into one lump for about a year. To date, I've found a few devises that do most of what you're talking about very well, but no single box that does them all well.
What I have is a mess of goodies all linked through a wireless N/router and it does what I want it too. PM me if you want a list and schematic.
If you want to take the minimalist approach:
42" flat screen- I prefer Samsung for the price to quality ratio. 32's just not enough if you're more than 5' away.
PS3/move- Plays DVD/BD/CD/MP3 etc.., downloads Netflix, has a web browser, Move integrates a web cam (I'm pretty sure), HDMI interface and an optical digital audio output. Up to 320g internal drive and unlimited storage expansion. Get the DVD remote too, it's just easier. Oh and it plays games too.
Western digital- 2TB external usb drive. All the storage you'll need for a while, chain in another when you need more.
Logitech- Wireless laser mouse and Keyboard of choice, I like the MX3200 keyboard and the Performance MX mouse
Performance Mouse MX? . I have an older version with a couple more buttons added for Zoom. The back/forward buttons are priceless, the scroll wheel is revolutionary and I have the scroll wheel 'click' set to "open new tab". All of the heavily used browser functions at your finger tips, outstanding.
Cable internet connection-
Cisco or Linksys- wireless n/router, gives you virtually limitless internet connect-ability.
Any HTiB (Home theater in a box) that has HDMI, optical audio connect-ability and sounds good to you. HDMI is not necessary in the HTIB, but nice to have. Digital audio connect is a must. (PS3 and Samsung use Toslink optical cable, other brands may use a coaxial cable [not coax]). With HDMI to the TV and Toslink to the receiver, you have audio to both so you don't have to have the receiver on to hear the audio. Don't pay more for either cable, if it connects and work, it will sound/look just as good as the $200 cable on the rack next to it. -Unless your running the HDMI over 20', upgrade to a better quality cable to reduce signal loss-.
Ikea stand of choice.
2nd Subwoofer- 12"+ just because, one in the front and one in the back of a room is simply outstanding. And most HTIB's come with an underpowered 8" woofer, which is great for mid-bass and fill. But if you want to feel your bones vibrate you need size and power. This will probably cost more than any two of the above listed components, but it's worth every dime.
Comfortable chair-
Good supply of cereal-
The only draw back to this set-up is the processor in the PS3, it plays videos and games just fine, but web browsing is a little slow.
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