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There are two kinds of common .45.
.45 ACP: Most commonly used in semi-auto pistols and a few carbines/subguns. There are .45ACP revolvers: the Smith & Wesson and Colt "Victory" Model 1917 and Smith Mdl 25 are the best known. .45ACP requires half-moon or full-moon clips to work in most revolvers. .45ACP revolvers can also use the special .45 Auto Rim (which is nothing but a .45ACP cartridge with an old-fashioned rim for use in revolvers).
.45 Long Colt: 130+ years old and still kicking. The first of the true Big Bore American revolver rounds to achieve any commercial success. Still popular with Cowboy Action shooters, and used in various double-action Taurus and Smtih & Wesson revolvers still. Can be loaded to slightly exceed the .44 Remington Magnum, but these uber-hot loads should only be used with Ruger revolvers or very heavily-built lever-action rifles.
And that's not counting .45 Schofield, .455 Webley, .45 Win Mag or all the other oddball/obsolete .45 loadings out there.
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"I personally think that America's interests would be well served if after or at the time these clowns begin their revolting little hate crime the local police come in and cart them off on some trumped up charges or other. It is necessary in my opinion that America makes an example of them to the world."
--Strange Famous, advocating the use of falsified charges in order to shut people up.
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