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Here are a few that come to mind immediately:
Stress.
Increased physical exhertion.
Significant loss of weight.
Lack of sleep.
Significant changes in routine.
Change in medication.
Absence of an alpha female that usually kept her hormones on track.
Pre-menopause.
This is rare, and probably isn't happening to your girlfriend, but one of my friends faced pre-menopause symptoms starting at age 22. It started off with a missed period, then another. She finally decided to go see a physician and was put on hormone birth control to regulate her system. Not sure how well that worked for her, haven't asked, but she hasn't had any children.
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"Sometimes I have to remember that things are brought to me for a reason, either for my own lessons or for the benefit of others." Cynthetiq
"violence is no more or less real than non-violence." roachboy
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