View Single Post
Old 04-06-2009, 07:51 AM   #18 (permalink)
MSD
The sky calls to us ...
 
MSD's Avatar
 
Super Moderator
Location: CT
Quote:
Originally Posted by ChrisJericho View Post
Ok, so I went to the doctor today and she said I had sinusitus and prescribed me flonase to take for awhile. I can use it for a long time and there won't be such harsh side effects as the OTC nasal sprays.

So I'll see how this goes. It should take about 2-3 days before I feel the full effects. Thanks for everyone's imput.
Nasal corticosteroids are the only long-term solution. Local absorption is in the upper 90% range while absorption into the bloodstream is 1-3%

As peopel have said, pseudophedrine and oxymetazoline are great for occasional congestion only. Pseudophedrine not only induces rebound congestion, it causes a major spike in blood pressure after three to four days and produces diminishing returns at the same time, reverting to approximately placebo levels after roughly a week. At 10mg, Phenylephrine doesn't outperform placebo (unless you believe the GSK study that has an obvious incentive to find it effective. I think the dose you need is around 50mg, which has adverse effects if I'm remembering correctly.
MSD is offline  
 

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73