I don't know much about the Core 2 processor/motherboard series since I skipped that generation so I can't comment on that. One thing that stands out is the sound card. It retails at about $20. I'm looking at the cyberpower website and I think the MB you selected already has 7.1 audio. Also, the speaker set it comes with retails for about $15. First of all, I'm not a sound guy but I have doubts that a $20 sound card is really going to be much of an upgrade from the onboard sound. Furthermore, even if it is you won't notice it on the speakers that come with it. Definitely ask around but I think you might as well save the $30. Could you afford an extra $40? If so, maybe you could drop the sound card and upgrade the RAM to 8GB.
Did you see if you can get the setup with free shipping? It seems like there are lots of hidden ways to pay more or less depending on what base system you select. Play around with different starting points (including those more and less expensive than what you are looking for) selecting all the same components and make sure you end up with the cheapest final price.
One last thing, CP has a giveaway with Vista, be sure you go here and redeem your gift:
Buy Microsoft, Get More