I think Izzard would be more ikely to take a role asa villain than the Doctor.
The idea of Jim Nesbit is nteresting, and Coyle would be great -he's got the connections to the Moffat aparat, and was great in Coupling (the original UK version).
Also an option is Marc Warren.
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Overhead, the Albatross hangs motionless upon the air,
And deep beneath the rolling waves,
In labyrinths of Coral Caves,
The Echo of a distant time
Comes willowing across the sand;
And everthing is Green and Submarine
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