Stupid question - after you shut down everything - the Mac, the MyBook, everything - and plug it back in, do you see the device in Disk Utility, on the left? If not, then it's quite possible either the drive itself, or the cable, is bad. If it does, then you will need to Erase it again. I know the Mac will play nicely with the 1TB MyBook.
There's not a clicking or anything coming from the MyBook, is there? Do you have another system you plug the drive into?
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