In my opinion, American has a slightly better track record on safety. That's about the only discriminating factor I can think of.
Cancellations are almost always weather related. Occasionally you'll get equipment issues. And unless you have a crystal ball handy, you'll never be able to guess what's going to fly on time and what won't.
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"They that can give up essential liberty to obtain a little temporary safety deserve neither liberty nor safety." - B. Franklin
"There ought to be limits to freedom." - George W. Bush
"We have met the enemy and he is us." - Pogo
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