there's lots of choices...
the answer really depends on your budget. You can spend $40/month for a yahoo business account, to spending $10,000 for setup and design.
there are opensource things you can use like Zencart, but they require you to understand a bit more than the average person.
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I don't care if you are black, white, purple, green, Chinese, Japanese, Korean, hippie, cop, bum, admin, user, English, Irish, French, Catholic, Protestant, Jewish, Buddhist, Muslim, indian, cowboy, tall, short, fat, skinny, emo, punk, mod, rocker, straight, gay, lesbian, jock, nerd, geek, Democrat, Republican, Libertarian, Independent, driver, pedestrian, or bicyclist, either you're an asshole or you're not.
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