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Originally Posted by Cynthetiq
also, a virus caught by an adaware program? that's not normal.
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It's not as abnormal as you'd think. The algorithms that antispyware programs and antivirus programs use are very similar; there are even AS programs that use heuristics now, although I don't know if Spybot S&D has crossed that particular bridge yet. The line between various types of malware is getting fuzzier.
On to solving the problem.
First of all, don't panic. It does nothing to solve your problem.
Google tells me that prxchk is a utility for use with proxy servers. Whether it's actually malware or not is something I don't know, as I've never really investigated, although preliminary research seems to suggest that it's benign. You've managed to put it on your blacklist for registry changes in Spybot S&D, whether intentionally or by accident; to solve the problem, all you need to do is take it off the list. Follow the instructions in the link provided by Silent_Jay, replacing 'RealUpgrade' with 'prxchk' and report back if that doesn't solve your problem.
Note: backing up data is a very good idea in general and in this situation in particular. You may safely back up any mp3 files, txt files and jpg, bmp or png image files, as none of those are capable of carrying malicious code. Microsoft office file formats (.doc, etc) are susceptible to macro viruses, but they're pretty rare. No programs should be backed up (installers or other exes) as they're all potential vectors to spread a worm. The general rule of thumb is that data files are okay, program files are not, although that's not hard and fast. Several Microsoft file formats in particular are vulnerable to various types of malware. I'm also a big fan of keeping a liveboot cd handy (Knoppix, Ubuntu etc) for catastrophic failures. These will require you to learn the basics of navigating within Linux, but it's not that difficult and can potentially be a lifesaver in the event of a full OS crash.