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Originally Posted by willravel
LA is dry heat. Having lived in St. Louis and CA, I can say that dry heat is a lot worse.
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As an endurance athlete that's competed in the Deep South, the Southwest and Midwest, dry heat's got nothing on humidity. If it's going to be 90 degrees outside, I'd much rather have 25% humidity than 75% humidity. The ONLY time I've ever been in real danger of being hospitalized was after the Florida Relays 5k. That's one of only two track races where I have absolutely no recollection of the last mile, and I was a DNF (did not finish) because grabbed me when I started waivering between lanes in a straight.
If you live in Florida and don't use your air conditioner regularly, I'm man enough to admit that I couldn't do it.
/threadjack
QuasiMondo is right about the coefficient of friction and windows. Running your air conditioner in stopped traffic raises the RPM's than you'd otherwise have, but on the highway, it shouldn't really affect the MPG more than a few percentage points, which isn't going to be the big factor in this case.
Like I said before, driving a hybrid like an E320 isn't going to result in the best possible performance.