You're already ahead of the game when using FireFox. I'd use Norton or AVG antivirus (not both) and ad-aware plus spybot search and destroy. A combination of those with the windows firewall turned on will pretty much guarantee you won't get infected with any spyware or adware, much less viruses.
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"A Darwinian attacks his theory, seeking to find flaws. An ID believer defends his theory, seeking to conceal flaws." -Roger Ebert
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