What I would suggest is completely using separate disks for the OS and the Data. That way, if the OS fails, the data drives are still fine and vice versa. Use two harddrives in RAID 1 for the OS, 73gb would be fine. For the other 4 harddrive slots, you might choose either RAID 5 across 4 drives and then just use two partitions.....or.....you could have to more RAID 1 arrays each using two harddrives (one for data and one for user files or whatever).
I just like the fact that if the drives are separate, you don't have to reload the OS and recover the data, you just have to do one. As always though, get the machine the way you like it and make an image of the OS part at least.
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"You hear the one about the fella who died, went to the pearly gates? St. Peter let him in. Sees a guy in a suit making a closing argument. Says, "Who's that?" St. Peter says, "Oh, that's God. Thinks he's Denny Crane."
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