I believe that the reason Peter is sick was because of all the internal injuries that he sustained when he fell from the back of the stadium. He was in a hurry to protect Claire, so he had her run away, but he only had use of her powers for a short time, so he was unable to fully heal before she was out of range. I think that the explosion MAY be Peter, after he absorbs some of the NuclearGuy's powers, but is unable to control it, since it is new to him, so he overloads, but of course you KNOW they aren't gonna allow that to happen. NO WAY the network would actually allow a nuclear explosion in New York. So we KNOW that something is going to stop it.
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"It is not that I have failed, but that I have found 10,000 ways that it DOESN'T work!" --Thomas Edison
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