Deltona Couple, you said it.
I have both a handgun and a Surefire flashlight within reach. Never underestimate the effectiveness of a good flashlight in ruining an opponent's night-vision. You can test a high-output (e.g. 60-120 lumen) flashlight (these are not just maglights) in front of a mirror - it's like having a movie light in your face. An ideal home-defense firearm would have the light mounted on the pistol.
Just a small piece of advice. LEO friends of mine advised me against using "safety" ammunition (e.g. Glazer, BAT, Hydra-Shok, Starfire etc). The reason is that, if you happen to find yourself in a self-defense scenario (heaven forbid), which resulted in you shooting another person (say, a home invader) the use of non-standard "exotic" ammunition may make you look like some gun-nut homicidal vigilante to the jury/court/press. Similarly they advised against hand-loaded ammunition for the same reason.
Additionally, they advised that, ideally, you ought to practice with whatever ammunition you intend to use whenever possible. You don't want to find, at the critical moment, that JHPs misfeed in your weapon if you've been practicing with cheaper ball ammo. If you load JHPs you should practice as often as possible with JHPs at the range - if possible the same brand and loads. When I heard this advice I went to the range just to shoot out some of my Hydra-Shoks, Glazers (big fireball) and Starfires. Then I just purchased lots of ball ammo and just use those for both home defense and practice.
It's a tradeoff, I understand, since ball ammo will tend to go through walls and doors. But it's expensive to practice with JHPs all the time.
All in all I don't think it's a "grevious" mistake to use exotic ammo - because it is safer to use indoors. But the other factors ought to be considered.
Oh, and also try not to modify your defense weapon too much - outside of basic reliability. It might be a little tougher to be seen as a victim if you blasted a home invader to molecules with your .50 Browning M2HB Machine Gun.
hmmmm
This bedside table would be cool too ...