Everyone on here is going to have a different opinion on the "best" brands and calibers. All makes you listed are good. My advice: go to a range, shoot an assortment of different handguns, and pick the one that you like the best. Ultimately, you're the one who is going to be making the investment and spending the money on it, so what you choose for you might not be what others would choose for yourself. Personally for a dedicated self defense pistol I'd go with a double action revolver, but that's just my preference. Most places are going to have a big assortment in 9mm and .45 ammunition, and are carrying more and more .40 all the time. The places I've been to usually will have one or two types of 10mm, and that's about it. All have their followings.
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