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Cramps are usually caused by one of two things, dehydration and/or overexertion. I don't know of any study that links breathing technique with anything other than comfort, although a trainer or coach would definitely tell you to change to in through the nose out through the mouth. I would say monitor your pace and pulse rate, drink approx. 1 quart of water an hour for at least 2-3 hours prior to running, and avoid eating anything other than fruit within that 2-3 hour period.
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"Two roads diverged in a wood, and I-
I took the one less traveled by,
And that has made all the difference." - Robert Frost
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