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With the power off, check and see if the memory modules are seated property? Reboot your PC, after desktop is loaded, bring up Task Manger right away (Ctrl-Alt-Del) and leave it visible while you launch applications.
Do you run CPU/graphics intensive programs? Have you installed any new hardware/software? I had a system lockup and I found that the multi-card reader driver was causing the antivirus/spyware program (BitDenfender) to launch multiple instances of explorer.exe.
Under Task Manager - "Processes", it showed 2000+ tasks being run and eventurally it froze my system completely. I had to temporarily disable the antivirus, uninstalled the card reader driver before I was able to use my PC. Luckily I found an updated version of the driver and installed it. It doesn't cause BitDefender to lock up the computer anymore.
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