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Essentially other than the "normal" side effects of an opiate such as hydromorphone such as constipation, drowsiness and the like you shouldn't have anything internally damaged as you fear. The problem is your body will become dependant on it, and you'll have withdrawl problems such as you seem to know. The dose keeps going up because your body devlops a tolerance to it and the same dose no longer becomes effective.
When they take you off it it should be a step down type thing where you'll slowly lower your dose and/or space out the time between doses so you can come down more easily, going cold turkey would be bad, very bad, right up there with quitting heroin cold turkey, and I doubt you want to go through that.
For switching to another drug, it really won't make much of a difference. If you're requiring this high of a dose of hydromorphone our only real option would be to switch you to another opiate, which is just going to do the same thing to your body, the other painkillers out there are all akin to ibuprofen and the like, and aren't likely going to be enough for you if you're needing such high doses of hydromorphone.
As far as I know however, taking a dose that high shouldn't cause any organ damage or the like, your only problem is going to be withdrawing from it when the time comes.
Hope this helps and good luck!
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