If you want your snake to be nice and easy to handle then you should try to avoid feeding them live animals. as onesnowyowl mentioned live prey can hurt your snakes, mice can claw the snake ect. If you feed your snake live animals it will learn to hunt and will kind of hunt your hand when you stick it in the tank.
*edit. I have a friend with 2 boas and 2 pythons and both have no problem eating the pre-dead mice/rabbits. I am not sure if this is because of how they were raised or not
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