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Which pin? Depending on drive and cable, it may not cause problems. Three pins aren't used. Seven are grounds; losing one may or may not affect you. Another would slow you down to polled speeds.
Still, like the others said, careful.
BTW, pins are numbered 1-40 alternating between connector sides. Find the red stripe on the cable. Find the key on the connector. Pin 1 is on the end with the red stripe, opposite the key. Pin two is across from it, on the same side as the key. And so on.
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There are a vast number of people who are uninformed and heavily propagandized, but fundamentally decent. The propaganda that inundates them is effective when unchallenged, but much of it goes only skin deep. If they can be brought to raise questions and apply their decent instincts and basic intelligence, many people quickly escape the confines of the doctrinal system and are willing to do something to help others who are really suffering and oppressed." -Manufacturing Consent: Noam Chomsky and the Media, p. 195
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