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I'd say you should be able to mix them. I believe it's Excedrin Migraine that has the extra strength dosage of acetaminophen, ibuprofen, and aspirin all in one pill (plus caffine to help supercharge the aspirin).
If you were to do that with seperate pills, I'd do it moderately.
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"The truth is merely an excuse for lack of imagination." - Garak
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