I suppose any type of annoying behavior can ruin a relationship if it happens often enough, but there are three things I can think of that would cause me to immediately end a relationship:
1) Infidelity.
2) Domestic violence.
3) Committing a serious crime/violation of individual rights against me or someone else.
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"I am certain that nothing has done so much to destroy the safeguards of individual freedom as the striving after this mirage of social justice." - Friedrich Hayek
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