Quote:
From this data, it is clear that NE
circuits are dysregulated in affective disorders. These
abnormalities likely interfere with concentration, attention,
memory, arousal states, and sleep regulation. The primary dysfunction, if there indeed is one, in depression
is increasingly less likely to be found within the NE
system, per se; however, its dysregulation in the depressed
state apparently contributes to significant symptomatology,
and NE perturbation appears to be critical in treatment
response.
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Role of Norepinephrine in the Pathophysiology and
Treatment of Mood Disorders
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I got in a fight one time with a really big guy, and he said, "I'm going to mop the floor with your face." I said, "You'll be sorry." He said, "Oh, yeah? Why?" I said, "Well, you won't be able to get into the corners very well."
Emo Philips
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