No doubt that I'd open fire. To do any less would be to fail at a basic civic duty to remove the douchebag from society so that he cannot attack somebody else. And you can't know that the attacker would stop at a moderate beating. If you go around physically attacking people in violation of the law, you have to expect that people will not stand still for it, and that the cost may be your life.
As for "what point would you kill?" The answer is as soon as it's legally justified. Early Bird gets the Worm, and all that. As soon as the person puts you or your loved ones in danger, you MUST act, lest you lose the chance to act at all.
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