This is a long shot, but is it Wake, AKA Sillage? That had a (flatchested) female lead in a futuristic setting- she started out as a shipwrecked jungle wild child, but ended up working as an operative for Wake, a conglomeration of alien races that explore and refurbish planets for habitation. Her name was Navee/Navis.
http://sillage.scubay.com/home/menu.html