About Padme losing the will to live, wasn't that part of the prophesy? I might remember it wrong but I thought Palpatine knew she was going to die, he'd forseen it or something. Wasn't it out of anyone's control? An act of God or whatever their equivalent was. If the doctors and everyone else couldn't figure out why she was dying, they probably came to the conclusion that everything had turned to shit for her (with Anakin turning bad) and that she'd lost the will to live.
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